diff --git a/src/slic3r/GUI/AMSMaterialsSetting.cpp b/src/slic3r/GUI/AMSMaterialsSetting.cpp
index 19a32c2d21..034008a8fd 100644
--- a/src/slic3r/GUI/AMSMaterialsSetting.cpp
+++ b/src/slic3r/GUI/AMSMaterialsSetting.cpp
@@ -334,7 +334,7 @@ void AMSMaterialsSetting::create_panel_kn(wxWindow* parent)
     m_input_k_val->SetMinSize(wxSize(FromDIP(245), -1));
     m_input_k_val->SetMaxSize(wxSize(FromDIP(245), -1));
     m_input_k_val->GetTextCtrl()->SetValidator(wxTextValidator(wxFILTER_NUMERIC));
-    kn_val_sizer->Add(m_input_k_val, 0, wxALL | wxEXPAND | wxALIGN_CENTER_VERTICAL, FromDIP(0));
+    kn_val_sizer->Add(m_input_k_val, 0, wxALL | wxEXPAND, FromDIP(0));
 
     // n params input
     wxBoxSizer* n_sizer = new wxBoxSizer(wxHORIZONTAL);
@@ -345,7 +345,7 @@ void AMSMaterialsSetting::create_panel_kn(wxWindow* parent)
     kn_val_sizer->Add(m_n_param, 1, wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(5));
     m_input_n_val = new TextInput(parent, wxEmptyString, wxEmptyString, wxEmptyString, wxDefaultPosition, wxDefaultSize, wxTE_CENTRE | wxTE_PROCESS_ENTER);
     m_input_n_val->GetTextCtrl()->SetValidator(wxTextValidator(wxFILTER_NUMERIC));
-    kn_val_sizer->Add(m_input_n_val, 0, wxALL | wxEXPAND | wxALIGN_CENTER_VERTICAL, FromDIP(5));
+    kn_val_sizer->Add(m_input_n_val, 0, wxALL | wxEXPAND, FromDIP(5));
     m_n_param->Hide();
     m_input_n_val->Hide();
 
diff --git a/src/slic3r/GUI/AMSSetting.cpp b/src/slic3r/GUI/AMSSetting.cpp
index c28b588eb2..b8433b2656 100644
--- a/src/slic3r/GUI/AMSSetting.cpp
+++ b/src/slic3r/GUI/AMSSetting.cpp
@@ -618,7 +618,7 @@ void AMSSettingTypePanel::CreateGui()
     h_sizer->AddStretchSpacer();
     h_sizer->Add(m_type_combobox, 0, wxEXPAND);
     h_sizer->Add(m_switching_icon, 0, wxALIGN_CENTER);
-    h_sizer->Add(m_switching_tips, 0, wxEXPAND | wxLEFT | wxALIGN_CENTER, FromDIP(8));
+    h_sizer->Add(m_switching_tips, 0, wxEXPAND | wxLEFT, FromDIP(8));
     SetSizer(h_sizer);
     Layout();
     Fit();
@@ -754,7 +754,7 @@ void AMSSettingArrangeAMSOrder::CreateGui()
     m_btn_rearrange->Bind(wxEVT_BUTTON, &AMSSettingArrangeAMSOrder::OnBtnRearrangeClicked, this);
     h_sizer->Add(title, 0);
     h_sizer->AddStretchSpacer();
-    h_sizer->Add(m_btn_rearrange, 0, wxEXPAND | wxALIGN_CENTER_VERTICAL);
+    h_sizer->Add(m_btn_rearrange, 0, wxEXPAND);
     SetSizer(h_sizer);
     Layout();
     Fit();
diff --git a/src/slic3r/GUI/AmsMappingPopup.cpp b/src/slic3r/GUI/AmsMappingPopup.cpp
index bc9c52fc18..60ba9bd4f2 100644
--- a/src/slic3r/GUI/AmsMappingPopup.cpp
+++ b/src/slic3r/GUI/AmsMappingPopup.cpp
@@ -717,7 +717,7 @@ AmsMapingPopup::AmsMapingPopup(wxWindow *parent, bool use_in_sync_dialog) :
 
      m_sizer_ams_right_horizonal->AddStretchSpacer();
      m_sizer_ams_right_horizonal->AddSpacer(FromDIP(5));
-     m_sizer_ams_right_horizonal->Add(m_reset_btn, 0, wxALIGN_TOP | wxEXPAND );
+     m_sizer_ams_right_horizonal->Add(m_reset_btn, 0, wxEXPAND );
      m_reset_btn->Hide();
      m_right_first_text_panel->SetSizer(m_sizer_ams_right_horizonal);
      const int same_height = 15;
@@ -813,7 +813,7 @@ void AmsMapingPopup::msw_rescale()
     m_split_left_line->SetMaxSize(wxSize(-1, 1));
     sizer_split_ams->Add(0, 0, 0, wxEXPAND, 0);
     sizer_split_ams->Add(ams_title_text, 0, wxALIGN_CENTER, 0);
-    sizer_split_ams->Add(m_split_left_line, 1, wxALIGN_CENTER_VERTICAL | wxEXPAND, 0);
+    sizer_split_ams->Add(m_split_left_line, 1, wxEXPAND, 0);
     return sizer_split_ams;
  }
 
diff --git a/src/slic3r/GUI/BBLStatusBar.cpp b/src/slic3r/GUI/BBLStatusBar.cpp
index 385dd07123..175e553dc1 100644
--- a/src/slic3r/GUI/BBLStatusBar.cpp
+++ b/src/slic3r/GUI/BBLStatusBar.cpp
@@ -55,9 +55,9 @@ BBLStatusBar::BBLStatusBar(wxWindow *parent, int id)
         m_cancelbutton->Hide();
     });
 
-    m_sizer->Add(m_object_info_sizer, 1, wxEXPAND | wxALL | wxALIGN_LEFT, 5);
-    m_sizer->Add(m_slice_info_sizer, 1, wxEXPAND | wxALL | wxALIGN_LEFT, 5);
-    m_sizer->Add(m_status_text, 1, wxEXPAND | wxALL | wxALIGN_LEFT, 5);
+    m_sizer->Add(m_object_info_sizer, 1, wxEXPAND | wxALL, 5);
+    m_sizer->Add(m_slice_info_sizer, 1, wxEXPAND | wxALL, 5);
+    m_sizer->Add(m_status_text, 1, wxEXPAND | wxALL, 5);
     m_sizer->Add(m_prog, 0, wxEXPAND | wxLEFT | wxALL, 5);
     m_sizer->Add(m_cancelbutton, 0, wxEXPAND | wxALL, 5);
     m_sizer->SetSizeHints(m_self);
diff --git a/src/slic3r/GUI/CalibrationWizardPresetPage.cpp b/src/slic3r/GUI/CalibrationWizardPresetPage.cpp
index d944c8b2d1..ad62fd1aae 100644
--- a/src/slic3r/GUI/CalibrationWizardPresetPage.cpp
+++ b/src/slic3r/GUI/CalibrationWizardPresetPage.cpp
@@ -1139,8 +1139,8 @@ void CalibrationPresetPage::create_multi_extruder_filament_list_panel(wxWindow *
     else {
         m_main_sizer->GetStaticBox()->SetLabel(_L("Right Nozzle"));
         m_deputy_sizer->GetStaticBox()->SetLabel(_L("Left Nozzle"));
-        m_multi_exturder_ams_sizer->Add(m_deputy_sizer, 1, wxEXPAND | wxALL | wxALIGN_BOTTOM, 10);
-        m_multi_exturder_ams_sizer->Add(m_main_sizer, 1, wxEXPAND | wxALL | wxALIGN_BOTTOM, 10);
+        m_multi_exturder_ams_sizer->Add(m_deputy_sizer, 1, wxEXPAND | wxALL, 10);
+        m_multi_exturder_ams_sizer->Add(m_main_sizer, 1, wxEXPAND | wxALL, 10);
     }
     m_multi_extruder_ams_panel_sizer->Add(m_multi_exturder_ams_sizer);
 
@@ -2152,8 +2152,8 @@ void CalibrationPresetPage::init_with_machine(MachineObject* obj)
 
             m_main_sizer->GetStaticBox()->SetLabel(_L("Right Nozzle"));
             m_deputy_sizer->GetStaticBox()->SetLabel(_L("Left Nozzle"));
-            m_multi_exturder_ams_sizer->Add(m_deputy_sizer, 1, wxEXPAND | wxALL | wxALIGN_BOTTOM, 10);
-            m_multi_exturder_ams_sizer->Add(m_main_sizer, 1, wxEXPAND | wxALL | wxALIGN_BOTTOM, 10);
+            m_multi_exturder_ams_sizer->Add(m_deputy_sizer, 1, wxEXPAND | wxALL, 10);
+            m_multi_exturder_ams_sizer->Add(m_main_sizer, 1, wxEXPAND | wxALL, 10);
 
             m_main_extruder_on_left = false;
         }
@@ -2163,8 +2163,8 @@ void CalibrationPresetPage::init_with_machine(MachineObject* obj)
 
             m_main_sizer->GetStaticBox()->SetLabel(_L("Left Nozzle"));
             m_deputy_sizer->GetStaticBox()->SetLabel(_L("Right Nozzle"));
-            m_multi_exturder_ams_sizer->Add(m_main_sizer, 1, wxEXPAND | wxALL | wxALIGN_BOTTOM, 10);
-            m_multi_exturder_ams_sizer->Add(m_deputy_sizer, 1, wxEXPAND | wxALL | wxALIGN_BOTTOM, 10);
+            m_multi_exturder_ams_sizer->Add(m_main_sizer, 1, wxEXPAND | wxALL, 10);
+            m_multi_exturder_ams_sizer->Add(m_deputy_sizer, 1, wxEXPAND | wxALL, 10);
 
             m_main_extruder_on_left = true;
         }
diff --git a/src/slic3r/GUI/CameraPopup.cpp b/src/slic3r/GUI/CameraPopup.cpp
index 6d38182e33..9b4908b045 100644
--- a/src/slic3r/GUI/CameraPopup.cpp
+++ b/src/slic3r/GUI/CameraPopup.cpp
@@ -127,7 +127,7 @@ CameraPopup::CameraPopup(wxWindow *parent)
 
     top_sizer->Add(m_custom_camera_hint, 0, wxALIGN_CENTER_VERTICAL | wxALIGN_LEFT | wxALL, FromDIP(5));
     top_sizer->Add(0, 0, wxALL, 0);
-    top_sizer->Add(m_custom_camera_input, 2, wxALIGN_CENTER_VERTICAL | wxALIGN_LEFT | wxEXPAND | wxALL, FromDIP(5));
+    top_sizer->Add(m_custom_camera_input, 2, wxEXPAND | wxALL, FromDIP(5));
     top_sizer->Add(m_custom_camera_input_confirm, 1, wxALIGN_CENTER_VERTICAL | wxALIGN_RIGHT | wxALL, FromDIP(5));
     main_sizer->Add(top_sizer, 0, wxALL, FromDIP(10));
 
diff --git a/src/slic3r/GUI/CloneDialog.cpp b/src/slic3r/GUI/CloneDialog.cpp
index 1ee3a74341..4e3579070e 100644
--- a/src/slic3r/GUI/CloneDialog.cpp
+++ b/src/slic3r/GUI/CloneDialog.cpp
@@ -26,7 +26,7 @@ CloneDialog::CloneDialog(wxWindow *parent)
         ProcessEventLocally(e);
         e.Skip();
     });
-    f_sizer->Add(count_label  , 0, wxEXPAND | wxALIGN_CENTER_VERTICAL);
+    f_sizer->Add(count_label  , 0, wxEXPAND);
     f_sizer->Add(m_count_spin, 0, wxALIGN_CENTER_VERTICAL);
 
     auto arrange_label = new wxStaticText(this, wxID_ANY, _L("Auto arrange plate after cloning") + ":", wxDefaultPosition, wxDefaultSize, 0);
@@ -34,7 +34,7 @@ CloneDialog::CloneDialog(wxWindow *parent)
     m_arrange_cb = new ::CheckBox(this);
     m_arrange_cb->SetValue(m_config->get("auto_arrange") == "true");
 
-    f_sizer->Add(arrange_label, 0, wxEXPAND | wxALIGN_CENTER_VERTICAL);
+    f_sizer->Add(arrange_label, 0, wxEXPAND);
     f_sizer->Add(m_arrange_cb , 0, wxALIGN_CENTER_VERTICAL | wxTOP | wxBOTTOM, FromDIP(5));
 
     v_sizer->Add(f_sizer, 1, wxEXPAND | wxALL, FromDIP(10));
@@ -46,7 +46,7 @@ CloneDialog::CloneDialog(wxWindow *parent)
     m_progress->SetProgressForedColour(StateColor::darkModeColorFor(wxColour("#DFDFDF")));
     m_progress->SetDoubleBuffered(true);
     m_progress->Hide();
-    bottom_sizer->Add(m_progress, 2, wxEXPAND | wxLEFT | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    bottom_sizer->Add(m_progress, 2, wxEXPAND | wxLEFT, FromDIP(10));
 
     auto dlg_btns = new DialogButtons(this, {"Fill", "OK", "Cancel"}, "", 1 /*left_aligned*/);
 
diff --git a/src/slic3r/GUI/CreatePresetsDialog.cpp b/src/slic3r/GUI/CreatePresetsDialog.cpp
index 9a42319bf1..c3bf6f660f 100644
--- a/src/slic3r/GUI/CreatePresetsDialog.cpp
+++ b/src/slic3r/GUI/CreatePresetsDialog.cpp
@@ -767,7 +767,7 @@ wxBoxSizer *CreateFilamentPresetDialog::create_vendor_item()
     wxStaticText *static_vendor_text = new wxStaticText(this, wxID_ANY, _L("Vendor"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_vendor_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(5));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(5));
 
     // Convert all std::any to std::string
     std::vector<std::string> string_vendors;
@@ -808,7 +808,7 @@ wxBoxSizer *CreateFilamentPresetDialog::create_vendor_item()
         event.Skip();
     });
     m_filament_custom_vendor_input->Hide();
-    vendor_sizer->Add(textInputSizer, 0, wxEXPAND | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    vendor_sizer->Add(textInputSizer, 0, wxEXPAND, FromDIP(10));
 
     wxBoxSizer *comboBoxSizer      = new wxBoxSizer(wxVERTICAL);
     wxBoxSizer *checkbox_sizer     = new wxBoxSizer(wxHORIZONTAL);
@@ -845,7 +845,7 @@ wxBoxSizer *CreateFilamentPresetDialog::create_vendor_item()
 
     comboBoxSizer->Add(vendor_sizer, 0, wxEXPAND | wxTOP, FromDIP(5));
     comboBoxSizer->Add(checkbox_sizer, 0, wxEXPAND | wxTOP, FromDIP(5));
-    horizontal_sizer->Add(comboBoxSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(5));
+    horizontal_sizer->Add(comboBoxSizer, 0, wxEXPAND | wxALL, FromDIP(5));
 
     return horizontal_sizer;
 
@@ -859,7 +859,7 @@ wxBoxSizer *CreateFilamentPresetDialog::create_type_item()
     wxStaticText *static_type_text = new wxStaticText(this, wxID_ANY, _L("Type"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_type_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(5));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(5));
 
     wxArrayString filament_type;
     for (const wxString filament : m_system_filament_types_set) {
@@ -873,7 +873,7 @@ wxBoxSizer *CreateFilamentPresetDialog::create_type_item()
     m_filament_type_combobox->SetLabelColor(DEFAULT_PROMPT_TEXT_COLOUR);
     m_filament_type_combobox->Set(filament_type);
     comboBoxSizer->Add(m_filament_type_combobox, 0, wxEXPAND | wxALL, 0);
-    horizontal_sizer->Add(comboBoxSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(5));
+    horizontal_sizer->Add(comboBoxSizer, 0, wxEXPAND | wxALL, FromDIP(5));
 
     m_filament_type_combobox->Bind(wxEVT_COMBOBOX, [this](wxCommandEvent &e) {
         m_filament_type_combobox->SetLabelColor(*wxBLACK);
@@ -905,7 +905,7 @@ wxBoxSizer *CreateFilamentPresetDialog::create_serial_item()
     wxStaticText *static_serial_text = new wxStaticText(this, wxID_ANY, _L("Serial"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_serial_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(5));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(5));
 
     wxBoxSizer *comboBoxSizer = new wxBoxSizer(wxVERTICAL);
     m_filament_serial_input   = new TextInput(this, "", "", "", wxDefaultPosition, NAME_OPTION_COMBOBOX_SIZE, wxTE_PROCESS_ENTER);
@@ -924,7 +924,7 @@ wxBoxSizer *CreateFilamentPresetDialog::create_serial_item()
     static_eg_text->SetForegroundColour(wxColour("#6B6B6B"));
     static_eg_text->SetFont(::Label::Body_12);
     comboBoxSizer->Add(static_eg_text, 0, wxEXPAND | wxTOP, FromDIP(5));
-    horizontal_sizer->Add(comboBoxSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(5));
+    horizontal_sizer->Add(comboBoxSizer, 0, wxEXPAND | wxALL, FromDIP(5));
 
     return horizontal_sizer;
 }
@@ -937,7 +937,7 @@ wxBoxSizer *CreateFilamentPresetDialog::create_filament_preset_item()
     wxStaticText *static_filament_preset_text = new wxStaticText(this, wxID_ANY, _L("Filament Preset"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_filament_preset_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *  comboBoxSizer  = new wxBoxSizer(wxVERTICAL);
     comboBoxSizer->Add(create_radio_item(m_create_type.base_filament, this, wxEmptyString, m_create_type_btns), 0, wxEXPAND | wxALL, 0);
@@ -1012,7 +1012,7 @@ wxBoxSizer *CreateFilamentPresetDialog::create_filament_preset_item()
 
     comboBoxSizer->Add(create_radio_item(m_create_type.base_filament_preset, this, wxEmptyString, m_create_type_btns), 0, wxEXPAND | wxTOP, FromDIP(10));
 
-    horizontal_sizer->Add(comboBoxSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(comboBoxSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     horizontal_sizer->Add(0, 0, 0, wxLEFT, FromDIP(30));
 
@@ -1028,7 +1028,7 @@ wxBoxSizer *CreateFilamentPresetDialog::create_filament_preset_for_printer_item(
     m_filament_preset_panel->SetSize(PRINTER_LIST_SIZE);
     m_filament_presets_sizer = new wxGridSizer(3, FromDIP(5), FromDIP(5));
     m_filament_preset_panel->SetSizer(m_filament_presets_sizer);
-    vertical_sizer->Add(m_filament_preset_panel, 0, wxEXPAND | wxTOP | wxALIGN_CENTER_HORIZONTAL, FromDIP(5));
+    vertical_sizer->Add(m_filament_preset_panel, 0, wxEXPAND | wxTOP, FromDIP(5));
 
     return vertical_sizer;
 }
@@ -1644,16 +1644,16 @@ wxBoxSizer *CreatePrinterPresetDialog::create_step_switch_item()
     step_switch_panel->SetBackgroundColour(*wxWHITE);
     horizontal_sizer->Add(0, 0, 1, wxEXPAND,0);
     m_step_1 = new wxStaticBitmap(step_switch_panel, wxID_ANY, create_scaled_bitmap("step_1", nullptr, FromDIP(20)), wxDefaultPosition, wxDefaultSize);
-    horizontal_sizer->Add(m_step_1, 0, wxEXPAND | wxLEFT | wxRIGHT | wxALIGN_CENTER_VERTICAL, FromDIP(3));
+    horizontal_sizer->Add(m_step_1, 0, wxEXPAND | wxLEFT | wxRIGHT, FromDIP(3));
     wxStaticText *static_create_printer_text = new wxStaticText(step_switch_panel, wxID_ANY, m_create_type.create_printer, wxDefaultPosition, wxDefaultSize);
-    horizontal_sizer->Add(static_create_printer_text, 0, wxEXPAND | wxLEFT | wxRIGHT | wxALIGN_CENTER_VERTICAL, FromDIP(3));
+    horizontal_sizer->Add(static_create_printer_text, 0, wxEXPAND | wxLEFT | wxRIGHT, FromDIP(3));
     auto divider_line = new wxPanel(step_switch_panel, wxID_ANY, wxDefaultPosition, wxSize(FromDIP(50), 1));
     divider_line->SetBackgroundColour(PRINTER_LIST_COLOUR);
     horizontal_sizer->Add(divider_line, 0, wxLEFT | wxRIGHT | wxALIGN_CENTER_VERTICAL, FromDIP(3));
     m_step_2 = new wxStaticBitmap(step_switch_panel, wxID_ANY, create_scaled_bitmap("step_2_ready", nullptr, FromDIP(20)), wxDefaultPosition, wxDefaultSize);
-    horizontal_sizer->Add(m_step_2, 0, wxEXPAND | wxLEFT | wxRIGHT | wxALIGN_CENTER_VERTICAL, FromDIP(3));
+    horizontal_sizer->Add(m_step_2, 0, wxEXPAND | wxLEFT | wxRIGHT, FromDIP(3));
     wxStaticText *static_import_presets_text = new wxStaticText(step_switch_panel, wxID_ANY, _L("Import Preset"), wxDefaultPosition, wxDefaultSize);
-    horizontal_sizer->Add(static_import_presets_text, 0, wxEXPAND | wxLEFT | wxRIGHT | wxALIGN_CENTER_VERTICAL, FromDIP(3));
+    horizontal_sizer->Add(static_import_presets_text, 0, wxEXPAND | wxLEFT | wxRIGHT, FromDIP(3));
     horizontal_sizer->Add(0, 0, 1, wxEXPAND, 0);
 
     step_switch_panel->SetSizer(horizontal_sizer);
@@ -1704,13 +1704,13 @@ wxBoxSizer *CreatePrinterPresetDialog::create_type_item(wxWindow *parent)
     wxStaticText *static_serial_text = new wxStaticText(parent, wxID_ANY, _L("Create Type"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_serial_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *radioBoxSizer = new wxBoxSizer(wxVERTICAL);
 
     radioBoxSizer->Add(create_radio_item(m_create_type.create_printer, parent, wxEmptyString, m_create_type_btns), 0, wxEXPAND | wxALL, 0);
     radioBoxSizer->Add(create_radio_item(m_create_type.create_nozzle, parent, wxEmptyString, m_create_type_btns), 0, wxEXPAND | wxTOP, FromDIP(10));
-    horizontal_sizer->Add(radioBoxSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(radioBoxSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     return horizontal_sizer;
 }
@@ -1723,7 +1723,7 @@ wxBoxSizer *CreatePrinterPresetDialog::create_printer_item(wxWindow *parent)
     wxStaticText *static_vendor_text = new wxStaticText(parent, wxID_ANY, _L("Printer"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_vendor_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *vertical_sizer = new wxBoxSizer(wxVERTICAL);
     wxBoxSizer *comboBoxSizer = new wxBoxSizer(wxHORIZONTAL);
@@ -1851,7 +1851,7 @@ wxBoxSizer *CreatePrinterPresetDialog::create_printer_item(wxWindow *parent)
 
     vertical_sizer->Add(checkbox_sizer, 0, wxEXPAND | wxTOP, FromDIP(5));
 
-    horizontal_sizer->Add(vertical_sizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(vertical_sizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     return horizontal_sizer;
 
@@ -1865,7 +1865,7 @@ wxBoxSizer *CreatePrinterPresetDialog::create_nozzle_diameter_item(wxWindow *par
     wxStaticText *static_type_text = new wxStaticText(parent, wxID_ANY, _L("Nozzle Diameter"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_type_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *vertical_sizer = new wxBoxSizer(wxVERTICAL);
     wxBoxSizer *comboBoxSizer = new wxBoxSizer(wxHORIZONTAL);
@@ -1930,7 +1930,7 @@ wxBoxSizer *CreatePrinterPresetDialog::create_nozzle_diameter_item(wxWindow *par
     });
 
     vertical_sizer->Add(checkbox_sizer, 0, wxEXPAND | wxTOP, FromDIP(5));
-    horizontal_sizer->Add(vertical_sizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(vertical_sizer, 0, wxEXPAND | wxALL, FromDIP(10));
     horizontal_sizer->Add(0, 0, 0, wxEXPAND | wxLEFT, FromDIP(200));
 
     return horizontal_sizer;
@@ -1944,12 +1944,12 @@ wxBoxSizer *CreatePrinterPresetDialog::create_bed_shape_item(wxWindow *parent)
     wxStaticText *static_type_text = new wxStaticText(parent, wxID_ANY, _L("Bed Shape"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_type_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *  bed_shape_sizer       = new wxBoxSizer(wxVERTICAL);
     wxStaticText *static_bed_shape_text = new wxStaticText(parent, wxID_ANY, _L("Rectangle"), wxDefaultPosition, wxDefaultSize);
     bed_shape_sizer->Add(static_bed_shape_text, 0, wxEXPAND | wxALL, 0);
-    horizontal_sizer->Add(bed_shape_sizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(bed_shape_sizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     return horizontal_sizer;
 }
@@ -1962,26 +1962,26 @@ wxBoxSizer *CreatePrinterPresetDialog::create_bed_size_item(wxWindow *parent)
     wxStaticText *static_type_text = new wxStaticText(parent, wxID_ANY, _L("Printable Space"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_type_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *  length_sizer          = new wxBoxSizer(wxVERTICAL);
      // ORCA use icon on input box to match style with other Point fields
-    horizontal_sizer->Add(length_sizer, 0, wxEXPAND | wxLEFT | wxTOP | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(length_sizer, 0, wxEXPAND | wxLEFT | wxTOP, FromDIP(10));
     wxBoxSizer *length_input_sizer      = new wxBoxSizer(wxVERTICAL);
     m_bed_size_x_input = new TextInput(parent, "200", _L("mm"), "inputbox_x", wxDefaultPosition, PRINTER_SPACE_SIZE, wxTE_PROCESS_ENTER);
     wxTextValidator validator(wxFILTER_DIGITS);
     m_bed_size_x_input->GetTextCtrl()->SetValidator(validator);
     length_input_sizer->Add(m_bed_size_x_input, 0, wxEXPAND | wxLEFT, FromDIP(5));
-    horizontal_sizer->Add(length_input_sizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(5));
+    horizontal_sizer->Add(length_input_sizer, 0, wxEXPAND | wxALL, FromDIP(5));
 
     wxBoxSizer *  width_sizer      = new wxBoxSizer(wxVERTICAL);
     // ORCA use icon on input box to match style with other Point fields
-    horizontal_sizer->Add(width_sizer, 0, wxEXPAND | wxLEFT | wxTOP | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(width_sizer, 0, wxEXPAND | wxLEFT | wxTOP, FromDIP(10));
     wxBoxSizer *width_input_sizer      = new wxBoxSizer(wxVERTICAL);
     m_bed_size_y_input            = new TextInput(parent, "200", _L("mm"), "inputbox_y", wxDefaultPosition, PRINTER_SPACE_SIZE, wxTE_PROCESS_ENTER);
     m_bed_size_y_input->GetTextCtrl()->SetValidator(validator);
     width_input_sizer->Add(m_bed_size_y_input, 0, wxEXPAND | wxALL, 0);
-    horizontal_sizer->Add(width_input_sizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(5));
+    horizontal_sizer->Add(width_input_sizer, 0, wxEXPAND | wxALL, FromDIP(5));
 
     return horizontal_sizer;
 
@@ -1995,26 +1995,26 @@ wxBoxSizer *CreatePrinterPresetDialog::create_origin_item(wxWindow *parent)
     wxStaticText *static_type_text = new wxStaticText(parent, wxID_ANY, _L("Origin"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_type_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *  length_sizer       = new wxBoxSizer(wxVERTICAL);
     // ORCA use icon on input box to match style with other Point fields
-    horizontal_sizer->Add(length_sizer, 0, wxEXPAND | wxLEFT | wxTOP | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(length_sizer, 0, wxEXPAND | wxLEFT | wxTOP, FromDIP(10));
     wxBoxSizer *length_input_sizer = new wxBoxSizer(wxVERTICAL);
     m_bed_origin_x_input           = new TextInput(parent, "0", _L("mm"), "inputbox_x", wxDefaultPosition, PRINTER_SPACE_SIZE, wxTE_PROCESS_ENTER);
     wxTextValidator validator(wxFILTER_DIGITS);
     m_bed_origin_x_input->GetTextCtrl()->SetValidator(validator);
     length_input_sizer->Add(m_bed_origin_x_input, 0, wxEXPAND | wxLEFT, FromDIP(5)); // Align with other
-    horizontal_sizer->Add(length_input_sizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(5));
+    horizontal_sizer->Add(length_input_sizer, 0, wxEXPAND | wxALL, FromDIP(5));
 
     wxBoxSizer *  width_sizer       = new wxBoxSizer(wxVERTICAL);
     // ORCA use icon on input box to match style with other Point fields
-    horizontal_sizer->Add(width_sizer, 0, wxEXPAND | wxLEFT | wxTOP | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(width_sizer, 0, wxEXPAND | wxLEFT | wxTOP, FromDIP(10));
     wxBoxSizer *width_input_sizer = new wxBoxSizer(wxVERTICAL);
     m_bed_origin_y_input          = new TextInput(parent, "0", _L("mm"), "inputbox_y", wxDefaultPosition, PRINTER_SPACE_SIZE, wxTE_PROCESS_ENTER);
     m_bed_origin_y_input->GetTextCtrl()->SetValidator(validator);
     width_input_sizer->Add(m_bed_origin_y_input, 0, wxEXPAND | wxALL, 0);
-    horizontal_sizer->Add(width_input_sizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(5));
+    horizontal_sizer->Add(width_input_sizer, 0, wxEXPAND | wxALL, FromDIP(5));
 
     return horizontal_sizer;
 }
@@ -2027,7 +2027,7 @@ wxBoxSizer *CreatePrinterPresetDialog::create_hot_bed_stl_item(wxWindow *parent)
     wxStaticText *static_type_text = new wxStaticText(parent, wxID_ANY, _L("Hot Bed STL"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_type_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *hot_bed_stl_sizer = new wxBoxSizer(wxVERTICAL);
 
@@ -2037,11 +2037,11 @@ wxBoxSizer *CreatePrinterPresetDialog::create_hot_bed_stl_item(wxWindow *parent)
 
     hot_bed_stl_sizer->Add(m_button_bed_stl, 0, wxEXPAND | wxALL, 0);
 
-    horizontal_sizer->Add(hot_bed_stl_sizer, 0, wxEXPAND | wxLEFT | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(hot_bed_stl_sizer, 0, wxEXPAND | wxLEFT, FromDIP(10));
 
     m_upload_stl_tip_text = new wxStaticText(parent, wxID_ANY, "", wxDefaultPosition, wxDefaultSize);
     m_upload_stl_tip_text->SetLabelText(_L("Empty"));
-    horizontal_sizer->Add(m_upload_stl_tip_text, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(m_upload_stl_tip_text, 0, wxEXPAND | wxALL, FromDIP(10));
     return horizontal_sizer;
 }
 
@@ -2053,7 +2053,7 @@ wxBoxSizer *CreatePrinterPresetDialog::create_hot_bed_svg_item(wxWindow *parent)
     wxStaticText *static_type_text = new wxStaticText(parent, wxID_ANY, _L("Hot Bed SVG"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_type_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *hot_bed_stl_sizer = new wxBoxSizer(wxVERTICAL);
 
@@ -2063,11 +2063,11 @@ wxBoxSizer *CreatePrinterPresetDialog::create_hot_bed_svg_item(wxWindow *parent)
 
     hot_bed_stl_sizer->Add(m_button_bed_svg, 0, wxEXPAND | wxALL, 0);
 
-    horizontal_sizer->Add(hot_bed_stl_sizer, 0, wxEXPAND | wxLEFT | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(hot_bed_stl_sizer, 0, wxEXPAND | wxLEFT, FromDIP(10));
 
     m_upload_svg_tip_text = new wxStaticText(parent, wxID_ANY, "", wxDefaultPosition, wxDefaultSize);
     m_upload_svg_tip_text->SetLabelText(_L("Empty"));
-    horizontal_sizer->Add(m_upload_svg_tip_text, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(m_upload_svg_tip_text, 0, wxEXPAND | wxALL, FromDIP(10));
     return horizontal_sizer;
 }
 
@@ -2079,14 +2079,14 @@ wxBoxSizer *CreatePrinterPresetDialog::create_max_print_height_item(wxWindow *pa
     wxStaticText *static_type_text = new wxStaticText(parent, wxID_ANY, _L("Max Print Height"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_type_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *hight_input_sizer = new wxBoxSizer(wxVERTICAL);
     m_print_height_input          = new TextInput(parent, "200", _L("mm"), wxEmptyString, wxDefaultPosition, PRINTER_SPACE_SIZE, wxTE_PROCESS_ENTER); // Use same alignment with all other input boxes
     wxTextValidator validator(wxFILTER_DIGITS);
     m_print_height_input->GetTextCtrl()->SetValidator(validator);
     hight_input_sizer->Add(m_print_height_input, 0, wxEXPAND | wxLEFT, FromDIP(5));
-    horizontal_sizer->Add(hight_input_sizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(5));
+    horizontal_sizer->Add(hight_input_sizer, 0, wxEXPAND | wxALL, FromDIP(5));
 
     return horizontal_sizer;
 }
@@ -2592,7 +2592,7 @@ wxBoxSizer *CreatePrinterPresetDialog::create_printer_preset_item(wxWindow *pare
     wxStaticText *static_vendor_text = new wxStaticText(parent, wxID_ANY, _L("Printer Preset"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_vendor_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *  vertical_sizer = new wxBoxSizer(wxVERTICAL);
     wxStaticText *combobox_title = new wxStaticText(parent, wxID_ANY, m_create_type.base_curr_printer, wxDefaultPosition, wxDefaultSize, 0);
@@ -2625,7 +2625,7 @@ wxBoxSizer *CreatePrinterPresetDialog::create_printer_preset_item(wxWindow *pare
     comboBox_sizer->Add(m_printer_model, 0, wxEXPAND | wxLEFT, FromDIP(10));
     vertical_sizer->Add(comboBox_sizer, 0, wxEXPAND | wxTOP, FromDIP(5));
 
-    horizontal_sizer->Add(vertical_sizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(vertical_sizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     return horizontal_sizer;
 
@@ -2639,13 +2639,13 @@ wxBoxSizer *CreatePrinterPresetDialog::create_presets_item(wxWindow *parent)
     wxStaticText *static_serial_text = new wxStaticText(parent, wxID_ANY, _L("Presets"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_serial_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *radioBoxSizer = new wxBoxSizer(wxVERTICAL);
 
     radioBoxSizer->Add(create_radio_item(m_create_type.base_template, parent, wxEmptyString, m_create_presets_btns), 0, wxEXPAND | wxALL, 0);
     radioBoxSizer->Add(create_radio_item(m_create_type.base_curr_printer, parent, wxEmptyString, m_create_presets_btns), 0, wxEXPAND | wxTOP, FromDIP(10));
-    horizontal_sizer->Add(radioBoxSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(radioBoxSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     return horizontal_sizer;
 }
@@ -2731,7 +2731,7 @@ wxBoxSizer *CreatePrinterPresetDialog::create_presets_template_item(wxWindow *pa
     m_preset_template_panel->SetSizer(m_filament_sizer);
     m_scrooled_preset_sizer->Add(m_preset_template_panel, 0, wxEXPAND | wxALL, 0);
     m_scrolled_preset_window->SetSizerAndFit(m_scrooled_preset_sizer);
-    vertical_sizer->Add(m_scrolled_preset_window, 0, wxEXPAND | wxLEFT | wxRIGHT | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    vertical_sizer->Add(m_scrolled_preset_window, 0, wxEXPAND | wxLEFT | wxRIGHT, FromDIP(10));
 
     return vertical_sizer;
 }
@@ -3718,7 +3718,7 @@ wxBoxSizer *ExportConfigsDialog::create_export_config_item(wxWindow *parent)
     wxStaticText *static_serial_text = new wxStaticText(parent, wxID_ANY, _L("Presets"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(static_serial_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     wxBoxSizer *radioBoxSizer = new wxBoxSizer(wxVERTICAL);
 
@@ -3738,7 +3738,7 @@ wxBoxSizer *ExportConfigsDialog::create_export_config_item(wxWindow *parent)
     radioBoxSizer->Add(create_radio_item(m_exprot_type.printer_preset, parent, wxEmptyString, m_export_type_btns), 0, wxEXPAND | wxTOP, FromDIP(10));
     radioBoxSizer->Add(create_radio_item(m_exprot_type.filament_preset, parent, wxEmptyString, m_export_type_btns), 0, wxEXPAND | wxTOP, FromDIP(10));
     radioBoxSizer->Add(create_radio_item(m_exprot_type.process_preset, parent, wxEmptyString, m_export_type_btns), 0, wxEXPAND | wxTOP, FromDIP(10));
-    horizontal_sizer->Add(radioBoxSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(radioBoxSizer, 0, wxEXPAND | wxALL, FromDIP(10));
 
     return horizontal_sizer;
 }
@@ -4281,7 +4281,7 @@ wxBoxSizer *ExportConfigsDialog::create_select_printer(wxWindow *parent)
     m_serial_text           = new wxStaticText(parent, wxID_ANY, _L("Please select a type you want to export"), wxDefaultPosition, wxDefaultSize);
     optionSizer->Add(m_serial_text, 0, wxEXPAND | wxALL, 0);
     optionSizer->SetMinSize(OPTION_SIZE);
-    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    horizontal_sizer->Add(optionSizer, 0, wxEXPAND | wxALL, FromDIP(10));
     m_scrolled_preset_window = new wxScrolledWindow(parent);
     m_scrolled_preset_window->SetScrollRate(5, 5);
     m_scrolled_preset_window->SetBackgroundColour(*wxWHITE);
@@ -4450,7 +4450,7 @@ EditFilamentPresetDialog::EditFilamentPresetDialog(wxWindow *parent, Filamentinf
     m_main_sizer->Add(create_add_filament_btn(), 0, wxEXPAND | wxALL, 0);
     m_main_sizer->Add(create_preset_tree_sizer(), 0, wxEXPAND | wxALL, 0);
     m_note_text = new wxStaticText(this, wxID_ANY, _L("Note: If the only preset under this filament is deleted, the filament will be deleted after exiting the dialog."));
-    m_main_sizer->Add(m_note_text, 0, wxEXPAND | wxLEFT | wxRIGHT | wxBOTTOM | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    m_main_sizer->Add(m_note_text, 0, wxEXPAND | wxLEFT | wxRIGHT | wxBOTTOM, FromDIP(10));
     m_note_text->Hide();
     m_main_sizer->Add(create_dialog_buttons(), 0, wxEXPAND);
 
@@ -4652,31 +4652,31 @@ wxBoxSizer *EditFilamentPresetDialog::create_filament_basic_info()
     wxStaticText *static_vendor_text = new wxStaticText(this, wxID_ANY, _L("Vendor"), wxDefaultPosition, wxDefaultSize);
     vendor_key_sizer->Add(static_vendor_text, 0, wxEXPAND | wxALL, 0);
     vendor_key_sizer->SetMinSize(OPTION_SIZE);
-    vendor_sizer->Add(vendor_key_sizer, 0, wxEXPAND | wxLEFT | wxBOTTOM | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    vendor_sizer->Add(vendor_key_sizer, 0, wxEXPAND | wxLEFT | wxBOTTOM, FromDIP(10));
 
     wxBoxSizer *vendor_value_sizer = new wxBoxSizer(wxVERTICAL);
     wxStaticText *vendor_text = new wxStaticText(this, wxID_ANY, from_u8(m_vendor_name), wxDefaultPosition, wxDefaultSize);
     vendor_value_sizer->Add(vendor_text, 0, wxEXPAND | wxALL, 0);
-    vendor_sizer->Add(vendor_value_sizer, 0, wxEXPAND | wxLEFT | wxBOTTOM | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    vendor_sizer->Add(vendor_value_sizer, 0, wxEXPAND | wxLEFT | wxBOTTOM, FromDIP(10));
 
     //type
     wxBoxSizer *  type_key_sizer   = new wxBoxSizer(wxVERTICAL);
     wxStaticText *static_type_text = new wxStaticText(this, wxID_ANY, _L("Type"), wxDefaultPosition, wxDefaultSize);
     type_key_sizer->Add(static_type_text, 0, wxEXPAND | wxALL, 0);
     type_key_sizer->SetMinSize(OPTION_SIZE);
-    type_sizer->Add(type_key_sizer, 0, wxEXPAND | wxLEFT | wxBOTTOM | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    type_sizer->Add(type_key_sizer, 0, wxEXPAND | wxLEFT | wxBOTTOM, FromDIP(10));
 
     wxBoxSizer *  type_value_sizer = new wxBoxSizer(wxVERTICAL);
     wxStaticText *type_text        = new wxStaticText(this, wxID_ANY, from_u8(m_filament_type), wxDefaultPosition, wxDefaultSize);
     type_value_sizer->Add(type_text, 0, wxEXPAND | wxALL, 0);
-    type_sizer->Add(type_value_sizer, 0, wxEXPAND | wxLEFT | wxBOTTOM | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    type_sizer->Add(type_value_sizer, 0, wxEXPAND | wxLEFT | wxBOTTOM, FromDIP(10));
 
     //serial
     wxBoxSizer *  serial_key_sizer   = new wxBoxSizer(wxVERTICAL);
     wxStaticText *static_serial_text = new wxStaticText(this, wxID_ANY, _L("Serial"), wxDefaultPosition, wxDefaultSize);
     serial_key_sizer->Add(static_serial_text, 0, wxEXPAND | wxALL, 0);
     serial_key_sizer->SetMinSize(OPTION_SIZE);
-    serial_sizer->Add(serial_key_sizer, 0, wxEXPAND | wxLEFT | wxBOTTOM | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    serial_sizer->Add(serial_key_sizer, 0, wxEXPAND | wxLEFT | wxBOTTOM, FromDIP(10));
 
     wxBoxSizer *  serial_value_sizer = new wxBoxSizer(wxVERTICAL);
     wxString      full_filamnet_serial = from_u8(m_filament_serial);
@@ -4688,7 +4688,7 @@ wxBoxSizer *EditFilamentPresetDialog::create_filament_basic_info()
     wxToolTip *   toolTip     = new wxToolTip(full_filamnet_serial);
     serial_text->SetToolTip(toolTip);
     serial_value_sizer->Add(serial_text, 0, wxEXPAND | wxALL, 0);
-    serial_sizer->Add(serial_value_sizer, 0, wxEXPAND | wxLEFT | wxBOTTOM | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    serial_sizer->Add(serial_value_sizer, 0, wxEXPAND | wxLEFT | wxBOTTOM, FromDIP(10));
 
     basic_info_sizer->Add(vendor_sizer, 0, wxEXPAND | wxALL, 0);
     basic_info_sizer->Add(type_sizer, 0, wxEXPAND | wxALL, 0);
@@ -4735,7 +4735,7 @@ wxBoxSizer *EditFilamentPresetDialog::create_preset_tree_sizer()
     wxBoxSizer* m_preset_tree_window_sizer = new wxBoxSizer(wxVERTICAL);
     m_preset_tree_window_sizer->Add(m_preset_tree_panel, wxEXPAND | wxLEFT | wxRIGHT, FromDIP(10));
     m_preset_tree_window->SetSizerAndFit(m_preset_tree_window_sizer);
-    filament_preset_tree_sizer->Add(m_preset_tree_window, 0, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(10));
+    filament_preset_tree_sizer->Add(m_preset_tree_window, 0, wxEXPAND | wxALL, FromDIP(10));
 
     return filament_preset_tree_sizer;
 }
diff --git a/src/slic3r/GUI/Field.cpp b/src/slic3r/GUI/Field.cpp
index 93db4c32d2..bf3b2b8eda 100644
--- a/src/slic3r/GUI/Field.cpp
+++ b/src/slic3r/GUI/Field.cpp
@@ -2308,7 +2308,7 @@ void SliderCtrl::BUILD()
 	m_textctrl->SetFont(Slic3r::GUI::wxGetApp().normal_font());
 	m_textctrl->SetBackgroundStyle(wxBG_STYLE_PAINT);
 
-	temp->Add(m_slider, 1, wxEXPAND | wxALIGN_CENTER_VERTICAL, 0);
+	temp->Add(m_slider, 1, wxEXPAND, 0);
 	temp->Add(m_textctrl, 0, wxALIGN_CENTER_VERTICAL, 0);
 
 	m_slider->Bind(wxEVT_SLIDER, ([this](wxCommandEvent e) {
diff --git a/src/slic3r/GUI/FilamentMapDialog.cpp b/src/slic3r/GUI/FilamentMapDialog.cpp
index c0120c2c80..f765e94aa6 100644
--- a/src/slic3r/GUI/FilamentMapDialog.cpp
+++ b/src/slic3r/GUI/FilamentMapDialog.cpp
@@ -169,9 +169,9 @@ FilamentMapDialog::FilamentMapDialog(wxWindow                       *parent,
     else
         m_default_map_panel = nullptr;
 
-    panel_sizer->Add(m_manual_map_panel, 0, wxALIGN_CENTER | wxEXPAND);
-    panel_sizer->Add(m_auto_map_panel, 0, wxALIGN_CENTER | wxEXPAND);
-    if (show_default) panel_sizer->Add(m_default_map_panel, 0, wxALIGN_CENTER | wxEXPAND);
+    panel_sizer->Add(m_manual_map_panel, 0, wxEXPAND);
+    panel_sizer->Add(m_auto_map_panel, 0, wxEXPAND);
+    if (show_default) panel_sizer->Add(m_default_map_panel, 0, wxEXPAND);
     main_sizer->Add(panel_sizer, 0, wxEXPAND);
 
     wxPanel* bottom_panel = new wxPanel(this);
diff --git a/src/slic3r/GUI/FilamentMapPanel.cpp b/src/slic3r/GUI/FilamentMapPanel.cpp
index 0f0fba61ac..3727727a30 100644
--- a/src/slic3r/GUI/FilamentMapPanel.cpp
+++ b/src/slic3r/GUI/FilamentMapPanel.cpp
@@ -54,14 +54,14 @@ FilamentMapManualPanel::FilamentMapManualPanel(wxWindow                       *p
     m_right_panel->SetMinSize({ FromDIP(260),-1 });
 
     drag_sizer->AddStretchSpacer();
-    drag_sizer->Add(m_left_panel, 1, wxALIGN_CENTER | wxEXPAND);
+    drag_sizer->Add(m_left_panel, 1, wxEXPAND);
     drag_sizer->AddSpacer(FromDIP(7));
     drag_sizer->Add(m_switch_btn, 0, wxALIGN_CENTER | wxLEFT | wxRIGHT, FromDIP(1));
     drag_sizer->AddSpacer(FromDIP(7));
-    drag_sizer->Add(m_right_panel, 1, wxALIGN_CENTER | wxEXPAND);
+    drag_sizer->Add(m_right_panel, 1, wxEXPAND);
     drag_sizer->AddStretchSpacer();
 
-    top_sizer->Add(drag_sizer, 0, wxALIGN_CENTER | wxEXPAND);
+    top_sizer->Add(drag_sizer, 0, wxEXPAND);
 
     m_tips = new Label(this, _L("Tip: You can drag the filaments to reassign them to different nozzles."));
     m_tips->SetFont(Label::Body_14);
@@ -133,14 +133,14 @@ GUI::FilamentMapBtnPanel::FilamentMapBtnPanel(wxWindow *parent, const wxString &
 
     auto label_sizer = new wxBoxSizer(wxHORIZONTAL);
     label_sizer->AddStretchSpacer();
-    label_sizer->Add(m_btn, 0, wxALIGN_CENTER | wxEXPAND | wxLEFT, FromDIP(1));
-    label_sizer->Add(m_label, 0, wxALIGN_CENTER | wxEXPAND| wxALL, FromDIP(3));
+    label_sizer->Add(m_btn, 0, wxEXPAND | wxLEFT, FromDIP(1));
+    label_sizer->Add(m_label, 0, wxEXPAND| wxALL, FromDIP(3));
     label_sizer->AddStretchSpacer();
 
     m_disable_tip = new Label(this, _L("(Sync with printer)"));
 
     sizer->AddSpacer(FromDIP(32));
-    sizer->Add(label_sizer, 0, wxALIGN_CENTER | wxEXPAND);
+    sizer->Add(label_sizer, 0, wxEXPAND);
     sizer->Add(m_disable_tip, 0, wxALIGN_CENTER);
     sizer->AddSpacer(FromDIP(3));
 
@@ -154,7 +154,7 @@ GUI::FilamentMapBtnPanel::FilamentMapBtnPanel(wxWindow *parent, const wxString &
     detail_sizer->Add(m_detail, 0, wxALIGN_CENTER | wxLEFT | wxRIGHT, horizontal_margin);
     detail_sizer->AddStretchSpacer();
 
-    sizer->Add(detail_sizer, 0, wxALIGN_CENTER | wxEXPAND);
+    sizer->Add(detail_sizer, 0, wxEXPAND);
     sizer->AddSpacer(FromDIP(10));
 
     SetSizer(sizer);
@@ -364,7 +364,7 @@ FilamentMapDefaultPanel::FilamentMapDefaultPanel(wxWindow *parent) : wxPanel(par
     m_label->Wrap(FromDIP(500));
 
     sizer->AddStretchSpacer();
-    sizer->Add(m_label, 1, wxEXPAND | wxALIGN_CENTER);
+    sizer->Add(m_label, 1, wxEXPAND);
     sizer->AddStretchSpacer();
 
     SetSizerAndFit(sizer);
diff --git a/src/slic3r/GUI/ObjColorDialog.cpp b/src/slic3r/GUI/ObjColorDialog.cpp
index ced23a8d37..94b3e2cb08 100644
--- a/src/slic3r/GUI/ObjColorDialog.cpp
+++ b/src/slic3r/GUI/ObjColorDialog.cpp
@@ -57,7 +57,7 @@ wxBoxSizer* ObjColorDialog::create_btn_sizer(long flags,bool exist_error)
     m_button_list[wxOK]     = dlg_btns->GetOK();
     m_button_list[wxCANCEL] = dlg_btns->GetCANCEL();
 
-    btn_sizer->Add(dlg_btns, 0, wxEXPAND | wxALIGN_CENTER_VERTICAL);
+    btn_sizer->Add(dlg_btns, 0, wxEXPAND);
     return btn_sizer;
 }
 
@@ -310,8 +310,8 @@ ObjColorPanel::ObjColorPanel(wxWindow *parent, Slic3r::ObjDialogInOut &in_out, c
                                               wxBORDER_NONE | wxBU_AUTODRAW);
                 m_image_button->SetBitmap(image);
                 m_image_button->SetCanFocus(false);
-                icon_sizer->Add(m_image_button, 0, wxALIGN_CENTER_HORIZONTAL | wxALIGN_CENTER_VERTICAL | wxEXPAND | wxALL,
-                                FromDIP(0)); // wxALIGN_CENTER_HORIZONTAL | wxALIGN_CENTER_VERTICAL | wxEXPAND | wxALL
+                icon_sizer->Add(m_image_button, 0, wxEXPAND | wxALL,
+                                FromDIP(0)); // wxEXPAND | wxALL
                 cur_combox->Raise();//for mac
 
             m_sizer_simple->Add(icon_sizer, FromDIP(0), wxALIGN_CENTER | wxALL, FromDIP(0));
diff --git a/src/slic3r/GUI/PartSkipDialog.cpp b/src/slic3r/GUI/PartSkipDialog.cpp
index 051bb9b29c..12a794cfe2 100644
--- a/src/slic3r/GUI/PartSkipDialog.cpp
+++ b/src/slic3r/GUI/PartSkipDialog.cpp
@@ -197,9 +197,9 @@ PartSkipDialog::PartSkipDialog(wxWindow *parent) : DPIDialog(parent, wxID_ANY, _
 #else
     m_dlg_btn_sizer->Add(m_tot_label, 0, wxALIGN_CENTER_VERTICAL, 0);
 #endif
-    m_dlg_btn_sizer->Add(0, 0, 1, wxEXPAND | wxALIGN_CENTER_VERTICAL, FromDIP(0));
+    m_dlg_btn_sizer->Add(0, 0, 1, wxEXPAND, FromDIP(0));
     m_dlg_btn_sizer->Add(m_apply_btn, 0, wxALIGN_CENTER_VERTICAL, FromDIP(0));
-    m_dlg_btn_sizer->Add(0, 0, 0, wxLEFT | wxEXPAND | wxALIGN_CENTER_VERTICAL, FromDIP(24));
+    m_dlg_btn_sizer->Add(0, 0, 0, wxLEFT | wxEXPAND, FromDIP(24));
 
     m_dlg_placeholder = new wxPanel(m_book_third_panel, wxID_ANY, wxDefaultPosition, wxDefaultSize, wxTAB_TRAVERSAL);
     m_dlg_placeholder->SetMinSize(wxSize(-1, FromDIP(15)));
diff --git a/src/slic3r/GUI/PhysicalPrinterDialog.cpp b/src/slic3r/GUI/PhysicalPrinterDialog.cpp
index 8134e39cf9..1adbd3e2a6 100644
--- a/src/slic3r/GUI/PhysicalPrinterDialog.cpp
+++ b/src/slic3r/GUI/PhysicalPrinterDialog.cpp
@@ -384,7 +384,7 @@ void PhysicalPrinterDialog::build_printhost_settings(ConfigOptionsGroup* m_optgr
             auto txt = new wxStaticText(parent, wxID_ANY, from_u8((boost::format("%1%\n\t%2%") % info % ca_file_hint).str()));
             txt->SetFont(wxGetApp().normal_font());
             auto sizer = new wxBoxSizer(wxHORIZONTAL);
-            sizer->Add(txt, 1, wxEXPAND|wxALIGN_LEFT);
+            sizer->Add(txt, 1, wxEXPAND);
             return sizer;
         };
         m_optgroup->append_line(line);
diff --git a/src/slic3r/GUI/PlateSettingsDialog.cpp b/src/slic3r/GUI/PlateSettingsDialog.cpp
index 54887f9780..11847915e9 100644
--- a/src/slic3r/GUI/PlateSettingsDialog.cpp
+++ b/src/slic3r/GUI/PlateSettingsDialog.cpp
@@ -313,7 +313,7 @@ void OtherLayersSeqPanel::append_layer(const LayerSeqInfo* layer_info)
     single_layer_input_sizer->Add(end_layer_input, 0, wxLEFT | wxRIGHT | wxALIGN_CENTER, FromDIP(5));
     single_layer_input_sizer->AddStretchSpacer();
     single_layer_input_sizer->Add(drag_canvas, 0, wxLEFT | wxALIGN_CENTER, FromDIP(5));
-    layer_panel_sizer->Add(single_layer_input_sizer, 0, wxEXPAND | wxALIGN_CENTER | wxBOTTOM, FromDIP(10));
+    layer_panel_sizer->Add(single_layer_input_sizer, 0, wxEXPAND | wxBOTTOM, FromDIP(10));
     m_layer_input_sizer_list.push_back(single_layer_input_sizer);
     m_begin_layer_input_list.push_back(begin_layer_input);
     m_end_layer_input_list.push_back(end_layer_input);
diff --git a/src/slic3r/GUI/Plater.cpp b/src/slic3r/GUI/Plater.cpp
index 4534b0886a..206962279d 100644
--- a/src/slic3r/GUI/Plater.cpp
+++ b/src/slic3r/GUI/Plater.cpp
@@ -529,7 +529,7 @@ void Sidebar::priv::layout_printer(bool isBBL, bool isDual)
         //if (isBBL) {
             wxBoxSizer *hsizer = new wxBoxSizer(wxHORIZONTAL);
             hsizer->Add(image_printer, 0, wxLEFT  | wxALIGN_LEFT  | wxALIGN_CENTER_VERTICAL, FromDIP(10));
-            hsizer->Add(combo_printer, 1, wxEXPAND | wxALL | wxALIGN_LEFT | wxALIGN_CENTER_VERTICAL, FromDIP(2));
+            hsizer->Add(combo_printer, 1, wxEXPAND | wxALL, FromDIP(2));
             hsizer->AddSpacer(FromDIP(2));
             hsizer->Add(btn_edit_printer, 0, wxRIGHT | wxALIGN_RIGHT | wxALIGN_CENTER_VERTICAL, FromDIP(SidebarProps::IconSpacing()));
             //hsizer->Add(btn_connect_printer, 0, wxRIGHT | wxALIGN_RIGHT | wxALIGN_CENTER_VERTICAL, FromDIP(SidebarProps::IconSpacing()));
@@ -2186,7 +2186,7 @@ Sidebar::Sidebar(Plater *parent)
 
     auto search_sizer = new wxBoxSizer(wxHORIZONTAL);
     search_sizer->Add(new wxWindow(p->m_search_bar, wxID_ANY, wxDefaultPosition, wxSize(0, 0)), 0, wxEXPAND|wxLEFT|wxRIGHT, FromDIP(1));
-    search_sizer->Add(p->m_search_item, 1, wxEXPAND | wxALL | wxALIGN_CENTER_VERTICAL, FromDIP(2));
+    search_sizer->Add(p->m_search_item, 1, wxEXPAND | wxALL, FromDIP(2));
     p->m_search_bar->SetSizer(search_sizer);
     p->m_search_bar->Layout();
     search_sizer->Fit(p->m_search_bar);
diff --git a/src/slic3r/GUI/StatusPanel.cpp b/src/slic3r/GUI/StatusPanel.cpp
index 651e1c6f5b..1e9bc53f47 100644
--- a/src/slic3r/GUI/StatusPanel.cpp
+++ b/src/slic3r/GUI/StatusPanel.cpp
@@ -783,7 +783,7 @@ void PrintingTaskPanel::create_panel(wxWindow* parent)
     printingstage_horizontal_sizer->Add(m_printing_stage_value, 0, wxALIGN_LEFT | wxALIGN_CENTER_VERTICAL, 0);
     printingstage_horizontal_sizer->Add(m_question_button, 0, wxALIGN_CENTER_VERTICAL | wxLEFT, FromDIP(5));
     printingstage_vertical_sizer->Add(printingstage_horizontal_sizer, 0, wxALIGN_CENTER_VERTICAL, 0);
-    printingstage_vertical_sizer->Add(m_printing_stage_underline, 0, wxEXPAND |wxALIGN_TOP, 0);
+    printingstage_vertical_sizer->Add(m_printing_stage_underline, 0, wxEXPAND, 0);
     m_printing_stage_panel->SetSizer(printingstage_vertical_sizer);
 
     // Orca: display the end time of the print
@@ -2122,7 +2122,7 @@ wxBoxSizer* StatusBasePanel::create_filament_group(wxWindow* parent)
     });
 
 
-    sizer_box->Add(steps_sizer, 0, wxEXPAND | wxALIGN_LEFT | wxTOP, FromDIP(5));
+    sizer_box->Add(steps_sizer, 0, wxEXPAND | wxTOP, FromDIP(5));
     sizer_box->Add(m_button_retry, 0, wxLEFT, FromDIP(28));
     sizer_box->Add(0, 0, 0, wxTOP, FromDIP(5));
     m_filament_load_box->SetBackgroundColour(*wxWHITE);
diff --git a/src/slic3r/GUI/SyncAmsInfoDialog.cpp b/src/slic3r/GUI/SyncAmsInfoDialog.cpp
index 1e6f2256fe..b88c0d7605 100644
--- a/src/slic3r/GUI/SyncAmsInfoDialog.cpp
+++ b/src/slic3r/GUI/SyncAmsInfoDialog.cpp
@@ -495,7 +495,7 @@ void SyncAmsInfoDialog::add_two_image_control()
         m_swipe_left_button->SetBitmap(m_swipe_left_bmp_normal.bmp());
     });
     m_swipe_left_button->Bind(wxEVT_BUTTON, &SyncAmsInfoDialog::to_previous_plate, this);
-    swipe_left__sizer->Add(m_swipe_left_button, 0, wxALIGN_CENTER | wxEXPAND | wxALIGN_CENTER_VERTICAL);
+    swipe_left__sizer->Add(m_swipe_left_button, 0, wxEXPAND);
     swipe_left__sizer->AddStretchSpacer();
     view_two_thumbnail_sizer->Add(swipe_left__sizer, 0, wxEXPAND);
     view_two_thumbnail_sizer->AddSpacer(FromDIP(24));
@@ -507,19 +507,19 @@ void SyncAmsInfoDialog::add_two_image_control()
         m_left_image_button     = new wxButton(m_two_image_panel, wxID_ANY, {}, wxDefaultPosition, wxSize(FromDIP(LEFT_THUMBNAIL_SIZE_WIDTH), FromDIP(LEFT_THUMBNAIL_SIZE_WIDTH)),
                                            wxBORDER_NONE | wxBU_AUTODRAW);
         m_left_sizer_thumbnail = create_sizer_thumbnail(m_left_image_button, true);
-        m_two_image_panel_sizer->Add(m_left_sizer_thumbnail, FromDIP(0), wxALIGN_LEFT | wxEXPAND | wxLEFT | wxTOP | wxBOTTOM, FromDIP(8));
+        m_two_image_panel_sizer->Add(m_left_sizer_thumbnail, FromDIP(0), wxEXPAND | wxLEFT | wxTOP | wxBOTTOM, FromDIP(8));
         m_two_image_panel_sizer->AddSpacer(FromDIP(5));
 
         m_right_image_button = new wxButton(m_two_image_panel, wxID_ANY, {}, wxDefaultPosition,
                                             wxSize(FromDIP(RIGHT_THUMBNAIL_SIZE_WIDTH), FromDIP(RIGHT_THUMBNAIL_SIZE_WIDTH)),
                                             wxBORDER_NONE | wxBU_AUTODRAW);
         m_right_sizer_thumbnail = create_sizer_thumbnail(m_right_image_button, false);
-        m_two_image_panel_sizer->Add(m_right_sizer_thumbnail, FromDIP(0), wxALIGN_LEFT | wxEXPAND | wxRIGHT | wxTOP | wxBOTTOM, FromDIP(8));
+        m_two_image_panel_sizer->Add(m_right_sizer_thumbnail, FromDIP(0), wxEXPAND | wxRIGHT | wxTOP | wxBOTTOM, FromDIP(8));
         m_two_image_panel->SetSizer(m_two_image_panel_sizer);
         m_two_image_panel->Layout();
         m_two_image_panel->Fit();
 
-        view_two_thumbnail_sizer->Add(m_two_image_panel, FromDIP(0), wxALIGN_LEFT | wxEXPAND | wxTOP, FromDIP(2));
+        view_two_thumbnail_sizer->Add(m_two_image_panel, FromDIP(0), wxEXPAND | wxTOP, FromDIP(2));
     }
     view_two_thumbnail_sizer->AddSpacer(FromDIP(20));
     auto swipe_right__sizer = new wxBoxSizer(wxVERTICAL);
@@ -536,7 +536,7 @@ void SyncAmsInfoDialog::add_two_image_control()
     });
     m_swipe_right_button->Bind(wxEVT_BUTTON, &SyncAmsInfoDialog::to_next_plate, this);
 
-    swipe_right__sizer->Add(m_swipe_right_button, 0, wxALIGN_CENTER | wxEXPAND | wxALIGN_CENTER_VERTICAL);
+    swipe_right__sizer->Add(m_swipe_right_button, 0, wxEXPAND);
     swipe_right__sizer->AddStretchSpacer();
     view_two_thumbnail_sizer->Add(swipe_right__sizer, 0, wxEXPAND);
     view_two_thumbnail_sizer->AddStretchSpacer();
@@ -546,7 +546,7 @@ void SyncAmsInfoDialog::add_two_image_control()
     m_choose_plate_sizer->AddStretchSpacer();
 
     wxStaticText *chose_combox_title = new wxStaticText(m_two_thumbnail_panel, wxID_ANY, _CTX(L_CONTEXT("Plate", "Sync_AMS"), "Sync_AMS"));
-    m_choose_plate_sizer->Add(chose_combox_title, 0, wxALIGN_LEFT | wxALIGN_CENTER_VERTICAL | wxEXPAND | wxTOP, FromDIP(6));
+    m_choose_plate_sizer->Add(chose_combox_title, 0, wxEXPAND | wxTOP, FromDIP(6));
     m_choose_plate_sizer->AddSpacer(FromDIP(10));
 
     m_combobox_plate = new ComboBox(m_two_thumbnail_panel, wxID_ANY, wxEmptyString, wxDefaultPosition, wxSize(FromDIP(60), -1), 0, NULL, wxCB_READONLY);
@@ -563,7 +563,7 @@ void SyncAmsInfoDialog::add_two_image_control()
     m_two_thumbnail_panel->SetSizer(m_two_thumbnail_panel_sizer);
     m_two_thumbnail_panel->Layout();
     m_two_thumbnail_panel->Fit();
-    m_sizer_main->Add(m_two_thumbnail_panel, FromDIP(0), wxALIGN_CENTER | wxEXPAND | wxLEFT | wxRIGHT, FromDIP(25));
+    m_sizer_main->Add(m_two_thumbnail_panel, FromDIP(0), wxEXPAND | wxLEFT | wxRIGHT, FromDIP(25));
 
     update_swipe_button_state();
 }
@@ -717,9 +717,9 @@ SyncAmsInfoDialog::SyncAmsInfoDialog(wxWindow *parent, SyncInfo &info) :
         m_colormap_btn      = new CapsuleButton(m_scrolledWindow, PageType::ptColorMap, _L("Mapping"), true);
         m_override_btn      = new CapsuleButton(m_scrolledWindow, PageType::ptOverride, _L("Overwriting"), false);
         m_mode_combox_sizer->AddSpacer(SyncAmsInfoDialogWidth / 2.0f - FromDIP(8) / 2.0f - m_colormap_btn->GetSize().GetX());
-        m_mode_combox_sizer->Add(m_colormap_btn, 0, wxALIGN_CENTER | wxEXPAND | wxALL, FromDIP(2));
+        m_mode_combox_sizer->Add(m_colormap_btn, 0, wxEXPAND | wxALL, FromDIP(2));
         m_mode_combox_sizer->AddSpacer(FromDIP(8));
-        m_mode_combox_sizer->Add(m_override_btn, 0, wxALIGN_CENTER | wxEXPAND | wxALL, FromDIP(2));
+        m_mode_combox_sizer->Add(m_override_btn, 0, wxEXPAND | wxALL, FromDIP(2));
         m_mode_combox_sizer->AddSpacer(SyncAmsInfoDialogWidth / 2.0f - FromDIP(8) / 2.0f - m_override_btn->GetSize().GetX() - FromDIP(60));
         m_reset_all_btn = new ScalableButton(m_scrolledWindow, wxID_ANY, "reset_gray", wxEmptyString, wxDefaultSize, wxDefaultPosition, wxBU_EXACTFIT | wxNO_BORDER,
                                                         true, 14);
@@ -727,12 +727,12 @@ SyncAmsInfoDialog::SyncAmsInfoDialog(wxWindow *parent, SyncInfo &info) :
         m_reset_all_btn->SetBackgroundColour(*wxWHITE);
         m_reset_all_btn->SetToolTip(_L("Reset all filament mapping"));
 
-        m_mode_combox_sizer->Add(m_reset_all_btn, 0, wxALIGN_LEFT | wxEXPAND | wxALL, FromDIP(2));
+        m_mode_combox_sizer->Add(m_reset_all_btn, 0, wxEXPAND | wxALL, FromDIP(2));
 
         m_colormap_btn->Bind(wxEVT_BUTTON, &SyncAmsInfoDialog::update_when_change_map_mode,this); // update_when_change_map_mode(e.GetSelection());
         m_override_btn->Bind(wxEVT_BUTTON, &SyncAmsInfoDialog::update_when_change_map_mode,this);
 
-        bSizer->Add(m_mode_combox_sizer, FromDIP(0), wxEXPAND | wxALIGN_LEFT | wxTOP, FromDIP(10));
+        bSizer->Add(m_mode_combox_sizer, FromDIP(0), wxEXPAND | wxTOP, FromDIP(10));
     }
 
     m_basic_panel = new wxPanel(m_scrolledWindow, wxID_ANY, wxDefaultPosition, wxDefaultSize, wxTAB_TRAVERSAL);
diff --git a/src/slic3r/GUI/SysInfoDialog.cpp b/src/slic3r/GUI/SysInfoDialog.cpp
index 1e4fe64de2..933cfb4d7c 100644
--- a/src/slic3r/GUI/SysInfoDialog.cpp
+++ b/src/slic3r/GUI/SysInfoDialog.cpp
@@ -109,7 +109,7 @@ SysInfoDialog::SysInfoDialog()
         title_font.SetFamily(wxFONTFAMILY_ROMAN);
         title_font.SetPointSize(22);
         title->SetFont(title_font);
-        vsizer->Add(title, 0, wxEXPAND | wxALIGN_LEFT | wxTOP, wxGetApp().em_unit()/*50*/);
+        vsizer->Add(title, 0, wxEXPAND | wxTOP, wxGetApp().em_unit()/*50*/);
     }
 
     // main_info_text
diff --git a/src/slic3r/GUI/UpgradePanel.cpp b/src/slic3r/GUI/UpgradePanel.cpp
index 3a42f7343d..e4120ad70e 100644
--- a/src/slic3r/GUI/UpgradePanel.cpp
+++ b/src/slic3r/GUI/UpgradePanel.cpp
@@ -84,7 +84,7 @@ MachineInfoPanel::MachineInfoPanel(wxWindow* parent, wxWindowID id, const wxPoin
     m_staticText_sn = new wxStaticText(this, wxID_ANY, _L("Serial:"), wxDefaultPosition, wxDefaultSize, 0);
     m_staticText_sn->Wrap(-1);
     m_staticText_sn->SetFont(Label::Head_14);
-    m_ota_info_sizer->Add(m_staticText_sn, 0, wxALIGN_RIGHT | wxALL | wxEXPAND, FromDIP(5));
+    m_ota_info_sizer->Add(m_staticText_sn, 0, wxALL | wxEXPAND, FromDIP(5));
 
     m_staticText_sn_val = new wxStaticText(this, wxID_ANY, "-", wxDefaultPosition, wxDefaultSize, 0);
     m_staticText_sn_val->Wrap(-1);
diff --git a/src/slic3r/GUI/Widgets/AMSControl.cpp b/src/slic3r/GUI/Widgets/AMSControl.cpp
index 62b6d69fb7..396e8327e6 100644
--- a/src/slic3r/GUI/Widgets/AMSControl.cpp
+++ b/src/slic3r/GUI/Widgets/AMSControl.cpp
@@ -1078,7 +1078,7 @@ void AMSControl::createAmsPanel(wxSimplebook *parent, int &idx, std::vector<AMSi
             else{
                 auto ext_image = new AMSExtImage(book_panel, pos, m_total_ext_count, false);
                 book_sizer->Add(ams1, 0, wxLEFT, FromDIP(30));
-                book_sizer->Add(ext_image, 0, wxEXPAND | wxLEFT | wxALIGN_CENTER_VERTICAL, FromDIP(30));
+                book_sizer->Add(ext_image, 0, wxEXPAND | wxLEFT, FromDIP(30));
                 ext_image->setTotalExtNum(series_name, printer_type, total_ext_num);
                 m_ext_image_list[infos[0].ams_id] = ext_image;
             }